Chinese and Western Veterinary Drug Compatibility Taboo

Animal Drug Lincomycin Hydrochloride

Compatibility with metronidazole, enhanced efficacy.

In combination with roxithromycin and tilmicosin, the efficacy is reduced.

Compatibility with sulfonamides, turbidity, failure

Ampicillin, amoxicillin

With streptomycin, neomycin, polymyxin, quinolones and other compatibility, enhanced efficacy.

And tilmicosin, roxithromycin, doxycycline hydrochloride, florfenicol compatibility, reduced efficacy.

Compatible with Vc, Roxithromycin, it will precipitate, decomposition failure.

Compatibility with sulphonamides will precipitate and failure of decomposition.

Neomycin sulfate, gentamycin

Ampicillin, cephradine, cephalexin, doxycycline hydrochloride, TMP and other compatibility, enhanced efficacy.

And Vc, antibacterial weakened.

In combination with florfenicol, the efficacy is reduced.

With similar drugs, toxicity increases.

Roxithromycin, erythromycin thiocyanate, tilmicosin

With neomycin, gentamicin, florfenicol and other compatibility, enhanced efficacy.

And streptomycin, Lincomycin hydrochloride compatibility, curative effect.

With kanamycin, sulfa compatibility, increased toxicity.

In case of sodium chloride, calcium chloride, will precipitate and free base will precipitate

Chlortetracycline, doxycycline

With similar drugs, TMP compatibility, enhanced efficacy

In the presence of trivalent cations, insoluble complexes are formed

Florfenicol

With neomycin, doxycycline hydrochloride, colistin sulfate and other compatibility, enhanced efficacy.

With ampicillin, cephradine, cephalexin and other compatibility, the efficacy is reduced.

With kanamycin, streptomycin, sulfonamides, quinolones compatibility, increased toxicity.

Compatibility with VB12 inhibits erythropoiesis.

Norfloxacin Enrofloxacin Ciprofloxacin

And ampicillin, cephradine, cephalexin, streptomycin, neomycin, gentamicin, sulfa and other compatibility, enhanced efficacy.

With tetracycline, doxycycline hydrochloride, roxithromycin, florfenicol and other compatibility, the efficacy is reduced.

In case of metal cations, insoluble complexes will form.

Sulfonamides

Compatible with TMP, neomycin, gentamycin and kanamycin.

And ampicillin, cephalexin, cephradine compatibility, reduced efficacy.

With roxithromycin, florfenicol compatibility, increased toxicity

Clinical common antibiotics for injection include penicillin, streptomycin sulfate, kanamycin sulfate, and gentamicin sulfate. Penicillin G potassium and penicillin G sodium should not be related to tetracycline, oxytetracycline, kanamycin, gentamicin, sulfadiazine sodium, sodium bicarbonate, vitamin C, vitamin B1, noradrenergic, atropine, chlorpromazine, etc. Mixed use, penicillin G potassium than penicillin G sodium irritant, potassium concentration when the intravenous injection is too high or too fast, can cause hyperkalemia and cardiac arrest; ampicillin can not be with kanamycin, Qing The use of damycin, chloramphenicol, chlorpromazine hydrochloride, sodium bicarbonate, vitamin C, vitamin B1, 50g/L glucose, glucose saline;

Head cephalosporin bogey and aminoglycoside antibiotics such as streptomycin sulfate, kanamycin sulfate, gentamicin sulfate combined use, can not be compatible with saline or compound sodium oxide injection;

Sodium sulfadiazine injection is easy to precipitate in acidic solution with lower pH, and it can be used in combination with normal saline, compound sodium chloride injection, 200ml/L glycol and magnesium sulfate injection, and it is compatible with various drugs. Taboo.

Intravenous infusion of calcium chloride injection must be slow, avoid calcium swell, resulting in abnormal heart rate; This product has a strong irritant to the tissue, prevent leakage to the blood vessels outside the injection, so as to avoid local swelling or necrosis, if not careful Leakage should be immediately with a syringe to leak liquid, and then in the leakage of local injection of 250g/L sodium sulphate solution 10-25mL in order to form non-stimulating calcium sulfate, severe local incision should be handled; this product avoid and cardiac glycosides, adrenaline , Streptomycin sulfate, kanamycin sulfate, sulfadiazine sodium, dexamethasone sodium phosphate, magnesium sulfate injection combined; In addition, calcium chloride glucose injection and calcium gluconate injection is not the same kind of drug, can not be confused. Intravenous injection of calcium gluconate injection should also be slow, avoid and cardiac glycosides, epinephrine, sodium bicarbonate, CoA, magnesium sulfate injection and use.

Sodium bicarbonate injection is a basic drug, avoid use with acidic drugs; bicarbonate ions and calcium ions, magnesium ions, etc. form insoluble salts and precipitate, so this product is not mixed with calcium, magnesium ions injection; For patients suffering from heart failure, acute and chronic renal insufficiency, potassium deficiency and accompanied by retention of carbon dioxide should be used with caution; clinically inappropriate drugs compatible with sodium bicarbonate injection are hydrocortisone, vitamin K3, pethidine, Atropine sulfate, magnesium sulfate, chlorpromazine hydrochloride, penicillin G potassium, penicillin G sodium, compound sodium chloride, vitamin C, epinephrine, ATP, CoA, cytochrome C injection, etc.; generally, 50g/L Sodium is only compatible with dexamethasone sodium phosphate injection.

Potassium chloride injection is strictly prohibited when animal urine output is low or urine closure is not improved. Late chronic renal insufficiency and acute renal insufficiency should be used with caution. The concentration of intravenous drip should not be too high. The speed should not be too fast, otherwise it will inhibit myocardial contraction, and even lead to cardiac arrest; This product is not in clinical compatibility with adrenaline, sulfadiazine sodium injection, can be mixed with a variety of drugs.

Vitamin B1 should not be compatible with ampicillin, cephalosporins, o-chloramphenicol, chloramphenicol and other antibiotics; vitamin B1 has no clinical reports of incompatibility with any drug, vitamin K, not with barbiturates, Sodium bicarbonate, sodium penicillin G, procaine hydrochloride, chlorpromazine hydrochloride injection compatibility, vitamin C injection in alkaline solution is easily oxidized failure, it should not be mixed with strong alkaline injection, In addition should not be mixed with calcium, aminophylline, ampicillin, cephalosporins, tetracycline, kanamycin and other mixed injection.

Sulfa drugs and vitamin C in combination, will produce precipitates should not be compatible with the sodium plus injection of drugs kanamycin sulfate, oxytetracycline hydrochloride, tetracycline hydrochloride, chlorpromazine hydrochloride injection and so on.

Atropine solution Baidu Many people believe that atropine can solve 100 poison, in fact, atropine is used for organic phosphorus poisoning, and must be combined with the use of chlorine and phosphorus can completely detoxification.

[Incompatibility of veterinary drugs] ==

In the practice of clinical drug use, the ancients found that after some drugs were combined, they could produce toxicity or side effects, and summed up the "Eighteen Opposition" and "Nineteen Fears".

Eighteen anti-that is, veratrum and anti-ginseng, Codonopsis, Adenophora, Salvia miltiorrhiza, Sophora flavescens, Scrophulariaceae, Asarum, Paeonia, Aka Mother; Glycyrrhiza anti-big sorghum, alfalfa, seaweed, Ganzi.

Nineteen fears: sulfur phosporin nitrate (glauber salt); mercury fear alum cream (belief stone); wolf poisonous fear pilgrimage lice; crotons fear oxen (two ugly); lilac fear turmeric gold; dental nitrous oxide jingsanling; chuanwu, grass Wuyong rhino horn; ginseng fear Wulingzhi; Guan Gui (Guizhi, cinnamon) fear Chishili, white stone fat.

Freezing stiff pigs

During the production of pigs, due to various reasons, some stiff pigs (the masses are called old and young pigs) often appear or form. Such pigs eat less and grow slower; others only eat less. Affected the economic benefits of pig farming. In order to make everyone make a fortune in the Year of the Pig, the method of decompression is introduced as follows:

Deworming stomach

Trichlorfon is 0.017 grams per kilogram of body weight, once taken orally once a day for three days. After two days of deworming, 1 kg of lime was taken and dissolved in 5 kg of water. The pigs were fed with lime water and fed once a day for five days to remove eggs and various toxins in the gastrointestinal tract.

Stomach food

To get rid of stiff hogs completely, a big breakthrough must be made in digestive function. Each kilogram of body weight is made with rhubarb soda 1 (content 0.3g), and the maximum number of pigs per pig is no more than 10 pieces. The powder is fed once a day, and once a day, the stomach is used for five days. At the same time, each time 50 grams of hawthorn, malt, and Divine Comedy are used to feed the simmer sauce, once a day, even for five days. Tests have shown that the stiff pigs treated in this way have a strong appetite and greatly enhance their digestive function.

Feeding urine soy beans

Leave the bottom section with a bamboo tube, put 200 soy beans in the bamboo tube, and then fill in the urine. Soak it one day and one night. Feed it once in the morning on an empty stomach. The sow can continue to soak soybeans. One kilogram of soy beans can be eaten by a pig for three months.

After the ear root subcutaneous injection of vitamin AD drops each 5 ml (1500 units per milliliter containing vitamin A, containing vitamin D300 units), injected once a week, used three times.

Tim feeds "stone sulfur salt"

That is, lime, sulfur, salt and other equal amounts, first fry yellow salt and then pour lime into the fry for 10 minutes, add sulphur when the pot is cool, and make a total of powder and make it ready for bottling. Under 25 kilograms, 5 grams to 8 grams daily, 25 kilograms or more, daily serving 10 grams to 15 grams, until slaughtered. This not only supplements minerals but also stimulates appetite. It is an indispensable and important measure for fattening pigs.